ABSTRACT
PURPOSE: To assess the frequency and pattern of disc enhancement of lumbar spine on enhanced MR images and to determine whether enhanced MR images are useful for locating internal disc lesions. MATERIALS AND METHODS: MR images of a total of 225 discs from 45 patients were reviewed. Fifteen discs from 15 patients who had previously undergone an operation were excluded and 210 discs were therefore studied. T1-, T2-, and gadolinium-enhanced T1-weighted images were obtained after intravenous injection of Gd-DTPA(0.2 ml/kg). Findings were analyzed retrospectively. RESULTS: Sixty-nine(32.6%) of 210 discs showed enhancement. The pattern of enhancement was intradiscal(linear or nodular) or extradiscal. Of 165 morphologically normal discs, 34(20.6%) discs were enhanced; 32 showed linear and two showed nodular enhancement. All of six ruptured discs were enhanced. Six patients were operated on after MRI study ; one case of intradiscal linear enhancement revealed a bulging disc, three of five patients were confirmed on surgery as having ruptured discs in view of the extradiscal enhancement and the other two patients were confirmed having protruded discs. CONCLUSION: The pattern of disc enhancement is classifiedinto intradiscal and extradiscal. The former is further classified into linear and nodular. Gd-DTPA enhanced MRimages may be helpful in diagnosing ruptured discs and in detecting pathologic conditions in those patients whose discs appear to be morphologically normal before enhancement.
Subject(s)
Humans , Gadolinium DTPA , Injections, Intravenous , Magnetic Resonance Imaging , SpineABSTRACT
No abstract available.
ABSTRACT
Prostatic adenocarcinoma is a common genitourinary malignancy which frequently is assiciated with bony metastasis at initial diagnosis. The detection of bony metastasis is important because it often alters the therapeutic strategy. The radionuclide one scintigraphy is known to be the most sensitive diagnostic method in detecting bony metastasis from prostatic adenocarcinoma. In the histologic grading of prostatic adenocarcinoma, the Gleason's grading system is the most widely employed one which is based on the degree of glandular differentiation and the growth patterns of tumor in relation to the prostatic stroma. The purpose of this study is to know the correlation of Gleason's grade and bone scintigraphic findings in prostatic carcinoma. We analyzed 99mTc-diphosphonate bone scintigraphies of 19 cases with prostatic adenocarcinoma confirmed by transurethral prostatic biopsy. Ten of the 19 cases showed asymmetrical multiple radioisotope uptake suggesting bony metastases and their Gleason's grade were 4 or 5 in seven cases. The remaining three cases were Gleason's grade 2 or 3. Another nine cases showed symmetrical radioisotope uptake with normal renal imaging suggesting no bony metastases and their Gleason's grade were 1,2 or 3 in seven cases. The remaining two cases of these nine cases were Gleason's grade 4 and 5. As the results, there was a correlation between the Gleason's grade and bone scintigraphic findings. The asymmetrical multiple skeletal uptake of radioisotope may suggest that the Gleason's grade is likely to be higher.
Subject(s)
Adenocarcinoma , Biopsy , Diagnosis , Methods , Neoplasm Metastasis , Radionuclide ImagingABSTRACT
No abstract available.
Subject(s)
Brain , Craniocerebral Trauma , Head , Tomography, Emission-Computed, Single-PhotonABSTRACT
No abstract available.
Subject(s)
Brain , Technetium Tc 99m Exametazime , Thalamic Diseases , Tomography, Emission-Computed, Single-PhotonABSTRACT
No abstract available.
ABSTRACT
This investigation was aimed to study the effect of contrast media on the cardiovascular system. So in thisstudy, pithed rats were used whether alteration in cardiovascular system by contrast media were controlledcentrally. Furthermore, several hypertonic solutions were also used to clarify the effect of contrast media. Theresults are as follows: 1. Intravenous injection of contrast media in rats(2.5m/kg) caused hypotension andbradycardia. The effects were neither blocked by pretreatment of atropine nor pyribenzamine+atropine. 2. NaCl4.7%, dextrose 24.8%, urea 9.0% and glycerol 10.1%(v/v) which were equiosmolar with contrast media, causedhypotension, but did not affect the heart rate. 3. In pithed rats, intravenous injection of Angiografin increasedblood pressure in a dose-dependant manner, and caused decrease in heart rate compared with those of control rats. 4. In pithed rats, bradycardia by intravascular injection with Angiografin was partialy blocked by atropine. 5.Metrizamide of which iodine content was adjusted to 280 mg/ml caused increased in blood pressure when was injectedintravenously in pithed rats with little effect on heart rate. 6. When perfused with contrast media in rathindlimb at 15ml/kg speed both perfusion pressure and flow effluent incereased, simultaneously. These resultssuggest that hypotension might be caused by the central effect due to hyperosmolarity of contrast media andbrachycardia caused by both parasympathetic stimulation and direct inhibitory action on the cardiac conductivesystem.
Subject(s)
Animals , Rats , Atropine , Blood Pressure , Bradycardia , Cardiovascular System , Contrast Media , Diatrizoate Meglumine , Glucose , Glycerol , Heart Rate , Hypertonic Solutions , Hypotension , Injections, Intravenous , Iodine , Perfusion , UreaABSTRACT
Hypernephroma comprises about 85-90% of renal malignancy in adults. The natural course of hypernephroma isvery diverse and unpredictable from abrupt explosive growth with wide spread metastasis to asymptomatic slowgrowth for several years. Reports from aliens indicated that hypernephroma with histopathological papillary growthpattern has better prognosis and more frequently hypovascular on renal angiography and less echogenic onultrasonography than non-papillary hypernephroma. Reviewed here retrospectively all the patients who were admittedand diagnosed as hypernephroma histopathologically at the Severance Hospital from March, 1973 through September,1984, in respective of angiographic vascularity, ultrasonographic echogenicity, histopathologic cell type andgrowth pattern, and following results were obtained. 1. The incidence of calcification in hypernephroma was 7cases out of 53 cases(13%). The incidence of hypernephroma according to cell type was clear cell type 20 cases(56%), mixed cell type 11 cases (31%), granular cell type 4 cases (11%), sarcomatous cell type 1 case(2%). Theincidence of hypernephroma according to growth pattern was papillary growth pattern 14 cases(45%) andnon-papillary growth pattern 17 cases(55%). 2. Renal angiographically, hypervascular hypernephroma was 19cases(73%), hypovascular hypernephromas was 6 cases(23%), all of which showed abnormal marginal vessels. 3.Angiographically hypervascular hypernephroma had high incidence of predominantly high echogenicity andangiographically hypervascular hypernephroma had high incidence of predominantly low echogenicity. 4. Clear celltype hypernephroma had high incidence of predominantly low echogenicity on ultrasonography. 5. Predominantly lowechogneic hypernephroma had high incidence of papillary growth pattern and predominantly high echogenichypernephroma had high incidence of non-papillary growth pattern. In summary, clear cell type hypernephroma hadhigh incidence of hypovascularity angiographically and hypovascularity on angiography was correlated withpredominantly low echogenicity on ultrasonography, and predominantly low echognicity had high incidence ofpapillary hypernephroma which was reported to have more good prognosis than non-papillary hypernephroma. So, itcan be suggested that if a hypernephroma show hypovascularity on angiography or predominantly low echogenicity onultrasonography, it has a good prognosis than hypervascular or predominantly high echogenic hypernephroma.
Subject(s)
Adult , Humans , Angiography , Carcinoma, Renal Cell , Emigrants and Immigrants , Incidence , Neoplasm Metastasis , Prognosis , Retrospective Studies , UltrasonographyABSTRACT
A total of 60 patients with Hymenolepis nana infection were treated with a single oral dose of praziquantel in two different dose levels. Twenty-nine cases treated with praziquantel in a single dose of 15 mg/kg body weight produced a 100% cure rate. On the otehr hand, 30 out of 31 patients who received a single dose of 25 mg/kg body weight cured completely, but only one case had counts of 200 EPG of feces in each tests on the 20th and 21st days after treatment. The cure rate was 96.8% and the mean egg reduction rate of 99.8 per cent was obtained. Side effects were mild and transitory. In a few cases, abdominal pain, vertigo, headache and diarrhea were complained in a few hours after medication. Clinial hematology, serum biochemistry and urinalysis were performed immediately before and the next day after treatment in all cases. There were no significant abnormalities detected in these tests.
Subject(s)
Hymenolepis nanaABSTRACT
The determination of carcinoembryonic antigen (CEA) in serum has been of much interest currently concomitant with the search for an immunologic diagnosis test. In this study, serum CEA values from 68 patients with histologically proved cervical carcinoma were determined by radioimmunoassay before or/and at two, intervals after radiotherapy. Fourteen patients of 68 had CEA values over 10ng per milliliter before treatment. The incidence of positive CEA values was higher in the advanced stages of disease. Three patients of five with CEA levels greater than 10ng per milliliter before treatment showed a drop of CEA levels to be1ow 10ng per milliliter seven weeks after treatment whereas two patients showed no change in CEA values at the end of radiotherapy. Two patients with palliative therapy showed no change in CEA values. The CEA test seems to be of little value for the early diagnosis and the evaluation of therapy in patients with cervical carcinoma but appears to be interesting for the surveillance of patients who have shown a drop of CEA level after therapy.